Plew (also spelled Plu) is a small unincorporated community in western Lawrence County, Missouri, United States. Plew is located on former U.S. Route 66, now Route 96.
A post office called Plew was established in 1893, and remained in operation until 1904. It is unknown why the name Plew was applied to this community.
Coordinates: 37°11′34″N 94°02′13″W / 37.19278°N 94.03694°W