Phenylalanine 4-hydroxylase

PAH

Phenylalanine hydroxylase.jpg

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1DMW, 1J8T, 1J8U, 1KW0, 1LRM, 1MMK, 1MMT, 1TDW, 1TG2, 2PAH, 3PAH, 4ANP, 5PAH, 6PAH, 5FII

Identifiers

PAH, PH, PKU, PKU1, phenylalanine hydroxylase

External IDs

OMIM: 612349 MGI: 97473 HomoloGene: 234 GeneCards: PAH

Gene ontology
Molecular function	• iron ion binding • phenylalanine 4-monooxygenase activity • metal ion binding • monooxygenase activity • catalytic activity • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen • oxidoreductase activity
Cellular component	• cytosol • extracellular exosome
Biological process	• catecholamine biosynthetic process • neurotransmitter biosynthetic process • L-phenylalanine catabolic process • cellular amino acid biosynthetic process • aromatic amino acid family metabolic process • metabolism • oxidation-reduction process
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE PAH 205719 s at fs.png

PBB GE PAH 217583 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


5053


18478


ENSG00000171759


ENSMUSG00000020051


P00439


P16331

RefSeq (mRNA)


NM_000277


NM_008777

RefSeq (protein)


NP_000268


NP_032803

Location (UCSC)

Chr 12: 102.84 – 102.96 Mb

Chr 10: 87.52 – 87.58 Mb

PubMed search

1DMW, 1J8T, 1J8U, 1KW0, 1LRM, 1MMK, 1MMT, 1TDW, 1TG2, 2PAH, 3PAH, 4ANP, 5PAH, 6PAH, 5FII

ENSG00000171759

ENSMUSG00000020051

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Wikipedia

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