Peroxisome proliferator-activated receptor delta

PPARD

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1GWX, 1Y0S, 2AWH, 2B50, 2BAW, 2ENV, 2GWX, 2J14, 2Q5G, 2XYJ, 2XYW, 2XYX, 2ZNP, 2ZNQ, 3D5F, 3DY6, 3ET2, 3GWX, 3GZ9, 3OZ0, 3PEQ, 3SP9, 3TKM

Identifiers

Aliases

PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB, peroxisome proliferator activated receptor delta

External IDs

MGI: 101884 HomoloGene: 4544 GeneCards: PPARD

Gene ontology
Molecular function	• sequence-specific DNA binding • transcription coactivator activity • zinc ion binding • metal ion binding • NF-kappaB binding • steroid hormone receptor activity • fatty acid binding • protein binding • linoleic acid binding • drug binding • protein heterodimerization activity • lipid binding • transcription factor activity, sequence-specific DNA binding • transcription factor binding • RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding • DNA binding • transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
Cellular component	• nucleoplasm • nuclear chromatin • nucleus
Biological process	• fatty acid catabolic process • positive regulation of myoblast proliferation • positive regulation of epidermis development • cell differentiation • negative regulation of smooth muscle cell proliferation • negative regulation of myoblast differentiation • regulation of transcription, DNA-templated • placenta development • regulation of transcription from RNA polymerase II promoter • negative regulation of smooth muscle cell migration • wound healing • mRNA transcription • cholesterol metabolic process • negative regulation of apoptotic process • response to glucose • response to activity • response to organic substance • generation of precursor metabolites and energy • regulation of fat cell differentiation • transcription, DNA-templated • positive regulation of transcription, DNA-templated • response to vitamin A • heart development • cell-substrate adhesion • keratinocyte proliferation • positive regulation of gene expression • proteoglycan metabolic process • regulation of cell proliferation • negative regulation of cell growth • fatty acid oxidation • positive regulation of cell proliferation • glucose metabolic process • phospholipid biosynthetic process • negative regulation of epithelial cell proliferation • positive regulation of skeletal muscle tissue regeneration • apoptotic signaling pathway • vitamin A metabolic process • positive regulation of phosphatidylinositol 3-kinase signaling • keratinocyte migration • adipose tissue development • transcription initiation from RNA polymerase II promoter • regulation of skeletal muscle satellite cell proliferation • positive regulation of fat cell differentiation • negative regulation of transcription, DNA-templated • negative regulation of inflammatory response • cellular response to lipopolysaccharide • cellular response to hypoxia • negative regulation of collagen biosynthetic process • glucose transport • positive regulation of insulin secretion • steroid hormone mediated signaling pathway • apoptotic process • cell proliferation • negative regulation of transcription from RNA polymerase II promoter • intracellular receptor signaling pathway • axon ensheathment • decidualization • fatty acid transport • embryo implantation • negative regulation of pri-miRNA transcription from RNA polymerase II promoter • lipid metabolic process • fatty acid beta-oxidation • positive regulation of blood vessel diameter
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


5467


19015

Ensembl


ENSG00000112033


ENSMUSG00000002250

UniProt


Q03181


P35396

RefSeq (mRNA)


NM_001171818 NM_001171819 NM_001171820 NM_006238 NM_177435


NM_011145

RefSeq (protein)


NP_001165289 NP_001165290 NP_001165291 NP_006229 NP_803184


NP_035275.1 NP_035275

Location (UCSC)

Chr 6: 35.34 – 35.43 Mb

Chr 17: 28.23 – 28.3 Mb

PubMed search

1GWX, 1Y0S, 2AWH, 2B50, 2BAW, 2ENV, 2GWX, 2J14, 2Q5G, 2XYJ, 2XYW, 2XYX, 2ZNP, 2ZNQ, 3D5F, 3DY6, 3ET2, 3GWX, 3GZ9, 3OZ0, 3PEQ, 3SP9, 3TKM

5467

19015

ENSG00000112033

...
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