Peregrine Bertie, 2nd Duke of Ancaster and Kesteven PC (29 April 1686 – 1 January 1742), styled The Honourable Peregrine Bertie between 1686 and 1704, Lord Willoughby de Eresby between 1704 and 1715 and Marquess of Lindsey between 1715 and 1723, was a British nobleman and statesman.
Bertie, who matriculated at Oxford in the late 17th century, graduated from that university in 1702. In 1708, he entered Parliament as MP for Lincolnshire, and was invested a Privy Counsellor that same year. He would serve in the House of Commons until he was summoned to the House of Lords by a writ of acceleration in his father's Barony of Willoughby de Eresby in 1715.
In June 1711, he married Jane Brownlow (d. 25 August 1736), daughter of Sir John Brownlow, 3rd Baronet, by whom he had seven children:
While serving as a Gentleman of the Bedchamber, Lord Willougby de Eresby inherited the rest of his father's titles on his death in 1723; he also inherited the hereditary Great Office of Lord Great Chamberlain and was made Lord Lieutenant of Lincolnshire in his late father's place. He had a seat on the Foundling Hospital's board of governors from the time of that charity's foundation in 1739. In 1742 he was made a Privy Counsellor. He served in these capacities, and also in the House of Lords, gaining the additional position of Lord Warden and Justice in Eyre until his death in 1742.