Paul James Krause (born February 19, 1942) is a former American football safety who played in the National Football League (NFL). He set the NFL record for interceptions with 81, which he picked off from 45 different quarterbacks, and was inducted into the Pro Football Hall of Fame in 1998.

Krause attended and played high school football at Bendle High School in Burton, Michigan and earned all-state honors in basketball, football, baseball and track. Known for once scoring 54 points in a basketball game, he was one of the few in his high school to ever receive an athletic scholarship.

Krause attended and played college football at the University of Iowa. He was a two-way starter as a wide receiver and defensive back. As a senior in 1963, he tied the Iowa record with six touchdown pass receptions and was selected for the Senior Bowl, the East-West Shrine game, the Coaches' All-American game and the College All-Star game.

Krause also played baseball at Iowa. As a sophomore, he earned All-American honors and was drafted into the major leagues, but he turned down the offer. Krause's chances to play professional baseball were ended when he injured his shoulder in his junior year playing football against the University of Michigan.

Krause was drafted in the second round of the 1964 NFL Draft by the Washington Redskins. In his rookie season, he led the NFL in interceptions with 12, including interceptions in seven straight games, and was named to the All-NFL first team. He was named to his first of eight Pro Bowls and was second only to teammate Charley Taylor for the NFL Rookie of the Year award.

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