Pasquale Orsini (born 1970) is an Italian palaeographer, librarian, and Professor from Università di Catania-Siracusa.
Orsini studied at the Sapienza University of Rome. He was a pupil of prof. Guglielmo Cavallo. He works at the Università di Catania-Siracusa. In 2004 he became a member of the Associazione Italiana Manoscritti Datati.
He examined and described Uncial 059, 082, 0321, and manuscripts housed in the Biblioteca Malatestiana, in Cesena.