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Parsonage–Turner syndrome

Parsonage–Turner syndrome
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The right brachial plexus with its short branches, viewed from in front.
Classification and external resources
Specialty neurology
ICD-10 G54.5
ICD-9-CM 353.5
DiseasesDB 32166
MeSH D020968
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Parsonage–Turner syndrome is also known as acute brachial neuropathy and acute brachial radiculitis. Other names used are Parsonage–Aldren–Turner syndrome, neuralgic amyotrophy,brachial neuritis, brachial plexus neuropathy, or brachial plexitis.

The syndrome is idiopathic; although many specific risk factors have been identified (such as; post-operatively, post-infectious, post-traumatic or post-vaccination), the etiology is still unknown. The condition manifests as a rare set of symptoms most likely resulting from autoimmune inflammation of unknown etiology of the brachial plexus. (The brachial plexus is a complex network of nerves through which impulses reach the arms, shoulders and chest.)

Parsonage–Turner syndrome has an incidence of 1.64 cases in 100,000 people.

Parsonage-Turner involves neuropathy of the suprascapular nerve in 97% of cases, and variably involves the axillary and subscapular nerves. As such, the muscles usually involved are the supraspinatus and infraspinatus, which are both innervated by the suprascapular nerve. Involvement of the deltoid is more variable, as it is innervated by the axillary nerve.

This syndrome can begin with severe shoulder or arm pain followed by weakness and numbness. Those who suffer from Parsonage–Turner experience acute, sudden-onset pain radiating from the shoulder to the upper arm. Affected muscles become weak and atrophied, and in advanced cases, paralyzed. Occasionally, there will be no pain and just paralysis, and sometimes just pain, not ending in paralysis.MRI may assist in diagnosis.

Despite its wasting and at times long-lasting effects, most cases resolve themselves and recovery is usually good in 18–24 months, depending on how old the person in question is. For instance, a six-year-old could have brachial neuritis for only around 6 months, but a person in their early fifties could have it for over 3 years.


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