Parathyroid hormone

PTH
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 1BWX, 1ET1, 1FVY, 1HPH, 1HPY, 1HTH, 1ZWA, 1ZWB, 1ZWD, 1ZWE, 1ZWF, 1ZWG, 2L1X, 3C4M
Identifiers
Aliases	PTH, PTH1, parathyroid hormone, Parathyroid hormone
External IDs	MGI: 97799 HomoloGene: 266 GeneCards: PTH
Gene ontology Molecular function • peptide hormone receptor binding • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding • parathyroid hormone receptor binding • type 1 parathyroid hormone receptor binding • hormone activity Cellular component • intracellular • cell • extracellular region • extracellular space Biological process • positive regulation of signal transduction • positive regulation of cell proliferation in bone marrow • positive regulation of osteoclast proliferation • response to drug • response to fibroblast growth factor • hormone-mediated apoptotic signaling pathway • cAMP metabolic process • response to ethanol • response to parathyroid hormone • skeletal system development • positive regulation of ossification • response to lead ion • response to nutrient levels • G-protein coupled receptor signaling pathway • response to vitamin D • negative regulation of apoptotic process in bone marrow • adenylate cyclase-activating G-protein coupled receptor signaling pathway • negative regulation of transcription from RNA polymerase II promoter • cellular macromolecule biosynthetic process • cellular calcium ion homeostasis • homeostasis of number of cells within a tissue • response to cadmium ion • Rho protein signal transduction • positive regulation of glucose import • positive regulation of glycogen biosynthetic process • bone resorption • positive regulation of cAMP biosynthetic process • positive regulation of bone mineralization • regulation of gene expression • positive regulation of transcription from RNA polymerase II promoter • cell-cell signaling Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5741	19226
Ensembl	ENSG00000152266	ENSMUSG00000059077
UniProt	P01270	n/a
RefSeq (mRNA)	NM_000315 NM_001316352	NM_020623
RefSeq (protein)	NP_000306 NP_001303281	n/a
Location (UCSC)	Chr 11: 13.49 – 13.5 Mb	Chr 7: 113.39 – 113.39 Mb
PubMed search

1BWX, 1ET1, 1FVY, 1HPH, 1HPY, 1HTH, 1ZWA, 1ZWB, 1ZWD, 1ZWE, 1ZWF, 1ZWG, 2L1X, 3C4M

5741

19226

ENSG00000152266

ENSMUSG00000059077

P01270

n/a

NM_000315
NM_001316352

NM_020623

NP_000306
NP_001303281

...
Wikipedia