CHGA | |||||||||||||||
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Identifiers | |||||||||||||||
Aliases | CHGA, CGA, chromogranin A | ||||||||||||||
External IDs | OMIM: 118910 MGI: 88394 HomoloGene: 976 GeneCards: CHGA | ||||||||||||||
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Species | Human | Mouse | |||||||||||||
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | Chr 14: 92.92 – 92.94 Mb | Chr 12: 102.55 – 102.57 Mb | |||||||||||||
PubMed search | |||||||||||||||
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ENSG00000276781
ENSG00000100604
NP_001266
NP_001288619
NP_001288619.1
Chromogranin A or parathyroid secretory protein 1 (gene name CHGA) is a member of the granin family of neuroendocrine secretory proteins, i.e., it is located in secretory vesicles of neurons and endocrine cells such as islet beta cell secretory granules in pancreas. In humans, chromogranin A protein is encoded by the CHGA gene.
Examples of cells producing chromogranin A (ChgA) are chromaffin cells of the adrenal medulla, paraganglia, enterochromaffin-like cells and beta cells of the pancreas. It is present in islet beta cell secretory granules.