PRDX1

PRDX1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2RII, 3HY2, 4XCS
Identifiers
Aliases	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Peroxiredoxin 1
External IDs	MGI: 99523 HomoloGene: 99789 GeneCards: PRDX1
Gene ontology Molecular function • antioxidant activity • protein binding • peroxiredoxin activity • identical protein binding • oxidoreductase activity • thioredoxin peroxidase activity • peroxidase activity • RNA binding • cadherin binding Cellular component • cytoplasm • cytosol • melanosome • myelin sheath • mitochondrion • extracellular exosome • nucleus • extracellular matrix • extracellular space Biological process • skeletal system development • response to reactive oxygen species • removal of superoxide radicals • response to oxidative stress • retina homeostasis • erythrocyte homeostasis • hydrogen peroxide catabolic process • regulation of NF-kappaB import into nucleus • cell proliferation • oxidation-reduction process • regulation of stress-activated MAPK cascade • natural killer cell mediated cytotoxicity • cell redox homeostasis Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5052	18477
Ensembl	ENSG00000117450	ENSMUSG00000028691
UniProt	Q06830	P35700
RefSeq (mRNA)	NM_181697 NM_001202431 NM_002574 NM_181696	NM_011034
RefSeq (protein)	NP_001189360 NP_002565 NP_859047 NP_859048	NP_035164.1 NP_035164
Location (UCSC)	Chr 1: 45.51 – 45.52 Mb	Chr 4: 116.69 – 116.7 Mb
PubMed search

2RII, 3HY2, 4XCS

5052

18477

ENSG00000117450

ENSMUSG00000028691

Q06830

P35700

NM_181697
NM_001202431
NM_002574
NM_181696

NM_011034

NP_001189360
NP_002565
NP_859047
NP_859048

NP_035164.1
NP_035164

Peroxiredoxin-1 is a protein that in humans is encoded by the PRDX1 gene.

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