PPP3R1

PPP3R1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1AUI, 1M63, 1MF8, 2P6B, 3LL8, 4F0Z, 4OR9, 4ORA, 4ORC, 4ORB
Identifiers
Aliases	PPP3R1, CALNB1, CNB, CNB1, protein phosphatase 3 regulatory subunit B, alpha
External IDs	MGI: 107172 HomoloGene: 68099 GeneCards: PPP3R1
Gene ontology Molecular function • calcium ion binding • protein domain specific binding • metal ion binding • calmodulin binding • protein binding • calcium-dependent protein serine/threonine phosphatase activity • phosphoprotein phosphatase activity Cellular component • cytoplasm • cytosol • membrane • plasma membrane • calcineurin complex • nucleoplasm • sarcolemma • mitochondrion Biological process • Fc-epsilon receptor signaling pathway • positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway • positive regulation of NFAT protein import into nucleus • positive regulation of transcription from RNA polymerase II promoter • protein dephosphorylation • Wnt signaling pathway, calcium modulating pathway • branching involved in blood vessel morphogenesis • epithelial to mesenchymal transition • heart development • Schwann cell development • myelination in peripheral nervous system • calcineurin-NFAT signaling cascade • protein localization to nucleus • NFAT protein import into nucleus • lung epithelial cell differentiation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	5534	19058
Ensembl	ENSG00000221823	ENSMUSG00000033953
UniProt	P63098	Q63810
RefSeq (mRNA)	NM_000945	NM_024459
RefSeq (protein)	NP_000936	NP_077779.2 NP_077779
Location (UCSC)	Chr 2: 68.18 – 68.26 Mb	Chr 11: 17.16 – 17.2 Mb
PubMed search

1AUI, 1M63, 1MF8, 2P6B, 3LL8, 4F0Z, 4OR9, 4ORA, 4ORC, 4ORB

5534

19058

ENSG00000221823

ENSMUSG00000033953

P63098

Q63810

NM_000945

NM_024459

NP_000936

NP_077779.2
NP_077779

Calcineurin subunit B type 1 also known as protein phosphatase 2B regulatory subunit 1 is a protein that in humans is encoded by the PPP3R1 gene.

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