PPP3CB

PPP3CB

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4OR9, 4ORA, 4ORC

Identifiers

PPP3CB, CALNA2, CALNB, CNA2, PP2Bbeta, protein phosphatase 3 catalytic subunit beta

External IDs

MGI: 107163 HomoloGene: 56429 GeneCards: PPP3CB

Gene location (Human)

Chr.	Chromosome 10 (human)

Band	10q22.2	Start	73,436,428 bp
Band	10q22.2	End	73,496,024 bp

Gene location (Mouse)

Chr.	Chromosome 14 (mouse)

Band	14\|14 A3	Start	20,499,364 bp
Band	14\|14 A3	End	20,546,573 bp

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• calcium ion binding • phosphoprotein phosphatase activity • protein dimerization activity • protein serine/threonine phosphatase activity • calmodulin-dependent protein phosphatase activity • metal ion binding • calmodulin binding • protein binding • drug binding • enzyme binding • protein phosphatase 2B binding • hydrolase activity
Cellular component	• cytosol • T-tubule • plasma membrane • calcineurin complex • nucleoplasm • Z disc
Biological process	• response to cytokine • lymphangiogenesis • regulation of insulin secretion • protein dephosphorylation • calcineurin-NFAT signaling cascade • memory • learning • regulation of synaptic plasticity • T cell homeostasis • positive regulation of transcription, DNA-templated • negative regulation of T cell mediated cytotoxicity • T cell proliferation • Fc-epsilon receptor signaling pathway • protein phosphorylation • heart development • T cell differentiation • cellular response to drug • axon extension • regulation of gene expression • social behavior • positive regulation of insulin secretion involved in cellular response to glucose stimulus • locomotion involved in locomotory behavior • T cell activation • positive regulation of transcription from RNA polymerase II promoter • calcium ion regulated exocytosis • signal transduction • dephosphorylation • Wnt signaling pathway, calcium modulating pathway
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


5532


19056


ENSG00000107758


ENSMUSG00000021816


P16298


P48453

RefSeq (mRNA)


NM_001142353 NM_001142354 NM_001289968 NM_001289969 NM_021132


NM_008914 NM_001310426 NM_001310427

RefSeq (protein)


NP_001135825 NP_001135826 NP_001276897 NP_001276898 NP_066955


NP_001297355 NP_001297356 NP_032940

Location (UCSC)

Chr 10: 73.44 – 73.5 Mb

Chr 10: 20.5 – 20.55 Mb

PubMed search

4OR9, 4ORA, 4ORC

ENSG00000107758

ENSMUSG00000021816

NM_001142353
NM_001142354
NM_001289968
NM_001289969
NM_021132

NM_008914
NM_001310426
NM_001310427

NP_001135825
NP_001135826
NP_001276897
NP_001276898
NP_066955

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Wikipedia

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