PPP1R12A

PPP1R12A

Protein PPP1R12A PDB 1s70.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2KJY, 2MXR, 5HUZ

Identifiers

PPP1R12A, M130, MBS, MYPT1, protein phosphatase 1 regulatory subunit 12A

External IDs

MGI: 1309528 HomoloGene: 1855 GeneCards: PPP1R12A

Gene ontology
Molecular function	• enzyme inhibitor activity • phosphatase regulator activity • 14-3-3 protein binding • signal transducer activity • protein binding • protein kinase binding
Cellular component	• centrosome • focal adhesion • nucleoplasm • Z disc • PTW/PP1 phosphatase complex • actin cytoskeleton • contractile fiber • A band • kinetochore • cytoplasm • cytosol
Biological process	• regulation of nucleocytoplasmic transport • positive regulation of myosin-light-chain-phosphatase activity • negative regulation of catalytic activity • cellular response to drug • regulation of cell adhesion • G2/M transition of mitotic cell cycle • regulation of myosin-light-chain-phosphatase activity • regulation of establishment of endothelial barrier • positive regulation of transcription from RNA polymerase II promoter • signal transduction • protein dephosphorylation • mitotic cell cycle • centrosome cycle
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE PPP1R12A 201603 at fs.png

PBB GE PPP1R12A 201604 s at fs.png

PBB GE PPP1R12A 201602 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


4659


17931


ENSG00000058272


ENSMUSG00000019907


O14974


Q9DBR7

RefSeq (mRNA)


NM_001143885 NM_001143886 NM_001244990 NM_001244992 NM_002480


NM_027892

RefSeq (protein)


NP_001137357 NP_001137358 NP_001231919 NP_001231921 NP_002471


NP_082168.1 NP_082168

Location (UCSC)

Chr 12: 79.77 – 79.94 Mb

Chr 10: 108.16 – 108.28 Mb

PubMed search

2KJY, 2MXR, 5HUZ

ENSG00000058272

ENSMUSG00000019907

NM_001143885
NM_001143886
NM_001244990
NM_001244992
NM_002480

NP_001137357
NP_001137358
NP_001231919
NP_001231921
NP_002471

NP_082168.1
NP_082168

...
Wikipedia

...