PPARGC1B

PPARGC1B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3SP6
Identifiers
Aliases	PPARGC1B, ERRL1, PERC, PGC-1(beta), PGC1B, PPARG coactivator 1 beta
External IDs	MGI: 2444934 HomoloGene: 15776 GeneCards: PPARGC1B
Genetically Related Diseases
obesity
Gene ontology Molecular function • RNA polymerase II transcription cofactor activity • AF-2 domain binding • receptor activator activity • ligand-dependent nuclear receptor transcription coactivator activity • RNA binding • nucleic acid binding • transcription cofactor activity • transcription factor binding • estrogen receptor binding Cellular component • mediator complex • nucleoplasm • mitochondrion • nucleus Biological process • transcription from mitochondrial promoter • regulation of transcription, DNA-templated • ossification • actin filament organization • mitochondrion organization • positive regulation of osteoclast differentiation • positive regulation of sequence-specific DNA binding transcription factor activity • response to glucocorticoid • bone trabecula formation • positive regulation of bone resorption • transcription, DNA-templated • positive regulation of transcription, DNA-templated • cellular response to reactive oxygen species • positive regulation of alkaline phosphatase activity • response to cAMP • positive regulation of phosphorylation • negative regulation of transcription, DNA-templated • intracellular estrogen receptor signaling pathway • positive regulation of transcription from RNA polymerase II promoter • positive regulation of receptor activity • regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	133522	170826
Ensembl	ENSG00000155846	ENSMUSG00000033871
UniProt	Q86YN6	Q8VHJ7
RefSeq (mRNA)	NM_001172698 NM_001172699 NM_133263	NM_133249
RefSeq (protein)	NP_001166169 NP_001166170 NP_573570	NP_573512.1 NP_573512
Location (UCSC)	Chr 5: 149.73 – 149.86 Mb	Chr 18: 61.3 – 61.4 Mb
PubMed search

3SP6

133522

170826

ENSG00000155846

ENSMUSG00000033871

Q86YN6

Q8VHJ7

NM_001172698
NM_001172699
NM_133263

NM_133249

NP_001166169
NP_001166170
NP_573570

NP_573512.1
NP_573512

Peroxisome proliferator-activated receptor gamma coactivator 1-beta is a protein that in humans is encoded by the PPARGC1B gene.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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