PLSCR1

PLSCR1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1Y2A
Identifiers
Aliases	PLSCR1, MMTRA1B, phospholipid scramblase 1
External IDs	MGI: 893575 HomoloGene: 41418 GeneCards: PLSCR1
Gene ontology Molecular function • phospholipid scramblase activity • DNA binding • calcium ion binding • CD4 receptor binding • SH3 domain binding • epidermal growth factor receptor binding • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • protein binding • enzyme binding Cellular component • integral component of membrane • cytosol • Golgi apparatus • membrane • extracellular matrix • plasma membrane • integral component of plasma membrane • nucleolus • membrane raft • extracellular exosome • nucleus Biological process • phosphatidylserine biosynthetic process • regulation of mast cell activation • phospholipid scrambling • positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity • response to interferon-beta • regulation of Fc receptor mediated stimulatory signaling pathway • platelet activation • negative regulation of viral genome replication • positive regulation of gene expression • defense response to virus • acute-phase response • positive regulation of innate immune response • positive regulation of transcription from RNA polymerase II promoter • apoptotic process • transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5359	22038
Ensembl	ENSG00000188313	ENSMUSG00000032369
UniProt	O15162	Q9JJ00
RefSeq (mRNA)	NM_021105	NM_011636
RefSeq (protein)	NP_066928	NP_035766
Location (UCSC)	Chr 3: 146.52 – 146.54 Mb	Chr 9: 92.25 – 92.27 Mb
PubMed search

1Y2A

5359

22038

ENSG00000188313

ENSMUSG00000032369

O15162

Q9JJ00

NM_021105

NM_011636

NP_066928

NP_035766

Phospholipid scramblase 1 is an enzyme that in humans is encoded by the PLSCR1 gene.

PLSCR1 has been shown to interact with:

...
Wikipedia