PKM2

PKM
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1T5A, 1ZJH, 3BJF, 3BJT, 3G2G, 3GQY, 3GR4, 3H6O, 3ME3, 3SRD, 3SRF, 3SRH, 3U2Z, 4B2D, 4FXF, 4FXJ, 4G1N, 4JPG, 4QG6, 4QG8, 4QG9, 4QGC, 4RPP, 4WJ8, 4YJ5
Identifiers
Aliases	PKM, CTHBP, HEL-S-30, OIP3, PK3, PKM2, TCB, THBP1, pyruvate kinase, muscle
External IDs	MGI: 97591 HomoloGene: 37650 GeneCards: PKM
Gene ontology Molecular function • transferase activity • nucleotide binding • potassium ion binding • metal ion binding • kinase activity • catalytic activity • protein binding • MHC class II protein complex binding • ATP binding • magnesium ion binding • pyruvate kinase activity • RNA binding • cadherin binding • identical protein binding • ADP binding • thyroid hormone binding Cellular component • cytoplasm • extracellular vesicle • vesicle • extracellular matrix • myelin sheath • cilium • mitochondrion • extracellular exosome • nucleus • extracellular region • cytosol • secretory granule lumen • ficolin-1-rich granule lumen • pyruvate kinase complex Biological process • glycolytic process • programmed cell death • phosphorylation • canonical glycolysis • metabolism • cellular response to insulin stimulus • neutrophil degranulation • response to hypoxia • liver development • glucose metabolic process • ATP biosynthetic process • response to nutrient • response to gravity • response to organic substance • response to muscle inactivity • animal organ regeneration • response to insulin • pyruvate biosynthetic process • skeletal muscle tissue regeneration • protein homotetramerization Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5315	18746
Ensembl	ENSG00000067225	ENSMUSG00000032294
UniProt	P14618	P52480
RefSeq (mRNA)	NM_001206796 NM_001206797 NM_001206798 NM_001206799 NM_002654 NM_182470 NM_182471 NM_001316318	NM_001253883 NM_011099
RefSeq (protein)	NP_001193725 NP_001193726 NP_001193727 NP_001193728 NP_001303247 NP_002645 NP_872270 NP_872271	NP_001240812 NP_035229
Location (UCSC)	Chr 15: 72.2 – 72.23 Mb	Chr 9: 59.66 – 59.68 Mb
PubMed search

1T5A, 1ZJH, 3BJF, 3BJT, 3G2G, 3GQY, 3GR4, 3H6O, 3ME3, 3SRD, 3SRF, 3SRH, 3U2Z, 4B2D, 4FXF, 4FXJ, 4G1N, 4JPG, 4QG6, 4QG8, 4QG9, 4QGC, 4RPP, 4WJ8, 4YJ5

5315

...
Wikipedia