PDPN

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3WSR, 4YO0

Identifiers

Aliases

PDPN, AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A, podoplanin

External IDs

MGI: 103098 HomoloGene: 4729 GeneCards: PDPN

Gene ontology
Molecular function	• folic acid transporter activity • water channel activity • amino acid transmembrane transporter activity • water transmembrane transporter activity • receptor binding • protein binding • chaperone binding • chemokine binding
Cellular component	• integral component of membrane • filopodium • ruffle • integral component of plasma membrane • external side of plasma membrane • lamellipodium • plasma membrane • cytosol • membrane • membrane raft • tetraspanin-enriched microdomain • basolateral plasma membrane • apical plasma membrane • lamellipodium membrane • cytoplasmic vesicle • filopodium membrane • microvillus membrane • ruffle membrane • cell projection • leading edge of lamellipodium • invadopodium
Biological process	• prostaglandin metabolic process • single organismal cell-cell adhesion • lymphangiogenesis • lung development • folic acid transport • water transport • platelet activation • multicellular organism development • regulation of G1/S transition of mitotic cell cycle • cell morphogenesis • regulation of cell shape • positive regulation of cellular component movement • lung alveolus development • cell proliferation • amino acid transport • signal transduction • positive regulation of epithelial to mesenchymal transition • positive regulation of cell migration • positive regulation of platelet aggregation • Rho protein signal transduction • wound healing, spreading of cells • positive regulation of extracellular matrix disassembly • invadopodium organization • regulation of lamellipodium morphogenesis • regulation of cell adhesion • negative regulation of cell proliferation • negative regulation of apoptotic process • lymph node development • lymphatic endothelial cell fate commitment • regulation of substrate adhesion-dependent cell spreading • regulation of myofibroblast contraction
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


10630


14726

Ensembl


ENSG00000162493


n/a

UniProt


Q86YL7


Q62011

RefSeq (mRNA)


NM_001006624 NM_001006625 NM_006474 NM_198389


NM_001290822 NM_010329

RefSeq (protein)


NP_001006625 NP_001006626 NP_006465 NP_938203


NP_001277751.1 NP_034459.2 NP_001277751 NP_034459

Location (UCSC)

Chr 1: 13.58 – 13.62 Mb

Chr 4: 143.27 – 143.3 Mb

PubMed search

n/a

NM_001006624
NM_001006625
NM_006474
NM_198389

NM_001290822
NM_010329

NP_001006625
NP_001006626
NP_006465
NP_938203

NP_001277751.1
NP_034459.2
NP_001277751
NP_034459

...
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