PDE4A

PDE4A

Protein PDE4A PDB 1loi.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2QYK, 3I8V, 3TVX

Identifiers

PDE4A, DPDE2, PDE4, PDE46, phosphodiesterase 4A

External IDs

MGI: 99558 HomoloGene: 4520 GeneCards: PDE4A

Gene ontology
Molecular function	• phosphoric diester hydrolase activity • cAMP binding • protein binding • hydrolase activity • 3',5'-cyclic-nucleotide phosphodiesterase activity • metal ion binding • 3',5'-cyclic-AMP phosphodiesterase activity
Cellular component	• cytoplasm • ruffle membrane • perinuclear region of cytoplasm • cytosol • cell projection • membrane • nucleoplasm • plasma membrane
Biological process	• sensory perception of smell • regulation of cAMP-mediated signaling • cellular response to drug • cAMP catabolic process • regulation of protein kinase A signaling • signal transduction
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE PDE4A 204735 at fs.png

PBB GE PDE4A 211447 s at fs.png

PBB GE PDE4A 211591 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


5141


18577


ENSG00000065989


ENSMUSG00000032177


P27815


O89084

RefSeq (mRNA)


NM_001111307 NM_001111308 NM_001111309 NM_001243121 NM_006202


NM_019798 NM_183408 NM_001310750

RefSeq (protein)


NP_001104777 NP_001104778 NP_001104779 NP_001230050 NP_006193


NP_001297679 NP_062772 NP_899668

Location (UCSC)

Chr 19: 10.42 – 10.47 Mb

Chr 9: 21.17 – 21.21 Mb

PubMed search

2QYK, 3I8V, 3TVX

ENSG00000065989

ENSMUSG00000032177

NM_001111307
NM_001111308
NM_001111309
NM_001243121
NM_006202

NM_019798
NM_183408
NM_001310750

NP_001104777
NP_001104778
NP_001104779
NP_001230050
NP_006193

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Wikipedia

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