PCAF

KAT2B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1CM0, 1JM4, 1N72, 1WUG, 1WUM, 1ZS5, 2RNW, 2RNX, 3GG3, 4NSQ, 5FE2, 5FE4, 5FDZ, 5FE8, 5FE5, 5FE1, 5FE7, 5FE9, 5FE3, 5FE0, 5FE6
Identifiers
Aliases	KAT2B, CAF, P/CAF, PCAF, lysine acetyltransferase 2B
External IDs	OMIM: 602303 MGI: 1343094 HomoloGene: 20834 GeneCards: KAT2B
Gene ontology Molecular function • transferase activity • RNA polymerase II regulatory region sequence-specific DNA binding • protein complex binding • N-acetyltransferase activity • transcription cofactor activity • protein binding • transferase activity, transferring acyl groups • histone acetyltransferase activity • cyclin-dependent protein serine/threonine kinase inhibitor activity • protein kinase binding • chromatin binding • lysine N-acetyltransferase activity, acting on acetyl phosphate as donor • transcription coactivator activity • transcription factor binding • histone deacetylase binding • acetyltransferase activity Cellular component • I band • nucleoplasm • PCAF complex • histone acetyltransferase complex • A band • actomyosin • kinetochore • Ada2/Gcn5/Ada3 transcription activator complex • nucleus Biological process • Notch signaling pathway • regulation of protein ADP-ribosylation • positive regulation of gene expression, epigenetic • chromatin remodeling • regulation of transcription, DNA-templated • negative regulation of cyclin-dependent protein serine/threonine kinase activity • rhythmic process • N-terminal peptidyl-lysine acetylation • transcription, DNA-templated • positive regulation of transcription, DNA-templated • histone acetylation • cell cycle arrest • histone H3 acetylation • cellular response to insulin stimulus • histone H3-K9 acetylation • cell cycle • transcription initiation from RNA polymerase II promoter • viral process • peptidyl-lysine acetylation • positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter • negative regulation of cell proliferation • positive regulation of transcription from RNA polymerase II promoter • internal peptidyl-lysine acetylation • protein acetylation • protein deubiquitination Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	8850	18519
Ensembl	ENSG00000114166	ENSMUSG00000000708
UniProt	Q92831	Q9JHD1
RefSeq (mRNA)	NM_003884	NM_001190846 NM_020005
RefSeq (protein)	NP_003875	NP_064389.2 NP_001177775 NP_064389
Location (UCSC)	Chr 3: 20.04 – 20.15 Mb	Chr 17: 53.57 – 53.67 Mb
PubMed search

1CM0, 1JM4, 1N72, 1WUG, 1WUM, 1ZS5, 2RNW, 2RNX, 3GG3, 4NSQ, 5FE2, 5FE4, 5FDZ, 5FE8, 5FE5, 5FE1, 5FE7, 5FE9, 5FE3, 5FE0, 5FE6

8850

18519

ENSG00000114166

ENSMUSG00000000708

...
Wikipedia