PAX6

PAX6

Protein PAX6 PDB 2cue.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2CUE, 6PAX

Identifiers

PAX6, AN, AN2, D11S812E, FVH1, MGDA, WAGR, paired box 6

External IDs

OMIM: 607108 MGI: 97490 HomoloGene: 1212 GeneCards: PAX6

Gene ontology
Molecular function	• protein binding • DNA binding • sequence-specific DNA binding • ubiquitin-protein transferase activity • RNA polymerase II core promoter sequence-specific DNA binding • RNA polymerase II transcription factor activity, sequence-specific DNA binding • transcription factor activity, sequence-specific DNA binding • transcription factor binding • protein kinase binding • histone acetyltransferase binding • R-SMAD binding
Cellular component	• cytoplasm • nucleus • nucleoplasm • cytosol • nuclear chromatin
Biological process	• eye development • blood vessel development • animal organ morphogenesis • regulation of transcription, DNA-templated • glucose homeostasis • transcription, DNA-templated • central nervous system development • response to wounding • cell differentiation • cornea development in camera-type eye • negative regulation of neurogenesis • visual perception • iris morphogenesis • multicellular organism development • neuron fate commitment • protein ubiquitination • pancreatic A cell development • transcription from RNA polymerase II promoter • positive regulation of gene expression • positive regulation of transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE PAX6 205646 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


5080


18508


ENSG00000007372


ENSMUSG00000027168


P26367


P63015

RefSeq (mRNA)

NM_000280 NM_001127612 NM_001258462 NM_001258463 NM_001258464
NM_001258465 NM_001310158 NM_001310159 NM_001310160 NM_001310161 NM_001604

NM_001244198 NM_001244200 NM_001244201 NM_001244202 NM_013627
NM_001310144 NM_001310145 NM_001310146

RefSeq (protein)

NP_000271 NP_001121084 NP_001245391 NP_001245392 NP_001245393
NP_001245394 NP_001297087 NP_001297088 NP_001297089 NP_001297090 NP_001595

NP_001231127.1 NP_001231129.1 NP_001231130.1 NP_001231131.1 NP_001297073.1
NP_001297074.1 NP_001297075.1 NP_038655.1 NP_001231127 NP_001231129 NP_001231130 NP_001231131 NP_001297073 NP_001297074 NP_001297075 NP_038655

Location (UCSC)

Chr 11: 31.78 – 31.82 Mb

Chr 2: 105.67 – 105.7 Mb

PubMed search

ENSG00000007372

ENSMUSG00000027168

NM_001258465
NM_001310158
NM_001310159
NM_001310160
NM_001310161
NM_001604

NM_001310144
NM_001310145
NM_001310146

NP_001245394
NP_001297087
NP_001297088
NP_001297089
NP_001297090
NP_001595

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Wikipedia

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