P2RY4

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2B6Q

Identifiers

Aliases

P2RY4, NRU, P2P, P2Y4, UNR, pyrimidinergic receptor P2Y4

External IDs

MGI: 1926594 HomoloGene: 20568 GeneCards: P2RY4

Gene ontology
Molecular function	• G-protein coupled purinergic nucleotide receptor activity • UTP-activated nucleotide receptor activity • ATP binding • G-protein coupled receptor activity • signal transducer activity • uridine nucleotide receptor activity
Cellular component	• integral component of membrane • plasma membrane • basolateral plasma membrane • integral component of plasma membrane • apical plasma membrane • membrane
Biological process	• positive regulation of cytosolic calcium ion concentration • phospholipase C-activating G-protein coupled receptor signaling pathway • G-protein coupled receptor signaling pathway • transepithelial chloride transport • signal transduction • G-protein coupled purinergic nucleotide receptor signaling pathway • cellular response to prostaglandin E stimulus
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


5030


57385

Ensembl


ENSG00000186912


ENSMUSG00000044359

UniProt


P51582


Q9JJS7

RefSeq (mRNA)


NM_002565


NM_020621

RefSeq (protein)


NP_002556


NP_065646

Location (UCSC)

Chr X: 70.26 – 70.26 Mb

Chr X: 100.59 – 100.59 Mb

PubMed search

P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.

The product of this gene, P2Y₄, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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