P2RY14

P2RY14
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2B6V
Identifiers
Aliases	P2RY14, BPR105, GPR105, P2Y14, purinergic receptor P2Y14
External IDs	MGI: 2155705 HomoloGene: 15769 GeneCards: P2RY14
Gene ontology Molecular function • G-protein coupled purinergic nucleotide receptor activity • UDP-activated nucleotide receptor activity • G-protein coupled receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • integral component of plasma membrane • membrane Biological process • G-protein coupled receptor signaling pathway • signal transduction • G-protein coupled purinergic nucleotide receptor signaling pathway Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9934	140795
Ensembl	ENSG00000174944	ENSMUSG00000036381
UniProt	Q15391	Q9ESG6
RefSeq (mRNA)	NM_001081455 NM_014879	NM_001008497 NM_001287119 NM_001287120 NM_001287121 NM_001287122 NM_001287123 NM_001287124 NM_133200
RefSeq (protein)	NP_001074924 NP_055694	NP_001008497 NP_001274048 NP_001274049 NP_001274050 NP_001274051 NP_001274052 NP_001274053 NP_573463
Location (UCSC)	Chr 3: 151.21 – 151.28 Mb	Chr 3: 59.11 – 59.15 Mb
PubMed search

2B6V

9934

140795

ENSG00000174944

ENSMUSG00000036381

Q15391

Q9ESG6

NM_001081455
NM_014879

NM_001287123
NM_001287124
NM_133200

NP_001074924
NP_055694

NP_001274052
NP_001274053
NP_573463

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.

The product of this gene, P2Y₁₄ belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.

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Wikipedia