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P-hydroxyphenylpyruvic acid

4-Hydroxyphenylpyruvic acid
4-hydroxyphenylpyruvic acid.svg
Names
IUPAC name
3-(4-hydroxyphenyl)-2-oxo-propanoic acid
Other names
4-Hydroxyphenylpyruvate
p-Hydroxyphenylpyruvic acid
p-Hydroxyphenylpyruvate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
DrugBank
ECHA InfoCard 100.005.322
KEGG
PubChem CID
Properties
C9H8O4
Molar mass 180.157 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YesYN ?)
Infobox references

4-Hydroxyphenylpyruvic acid (4-HPPA) is an intermediate in the metabolism of the amino acid phenylalanine. The aromatic side chain of phenylalanine is hydroxylated by the enzyme phenylalanine hydroxylase to form tyrosine. The conversion from tyrosine to 4-HPPA is in turn catalyzed by tyrosine aminotransferase. Additionally, 4-HPPA can be converted to homogentisic acid which is one of the precursors to ochronotic pigment.

It is an intermediary compound in the biosynthesis of scytonemin.



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