"Orange Crush" is a song by the American alternative rock band R.E.M. It was released as the first single from the band's sixth studio album, Green, in 1988. It was not commercially released in the U.S. despite reaching number one as a promotional single on both the Mainstream and Modern Rock Tracks (where, at the time, it had the record for longest stay at number one with eight weeks, beating U2). It peaked at number 28 on the UK Singles Chart, making it the band's then-highest chart hit in Britain, where they promoted the song by making their debut appearance on Top of the Pops.

The video for the song, directed by Matt Mahurin, won the band its first VMA, for Best Post-Modern Video. "Orange Crush" was also the first song to win in the category.

The song was placed on R.E.M.'s Warner Bros. Records compilation In Time: The Best of R.E.M. 1988–2003 in 2003, and a live version appears on the R.E.M. Live album recorded in Dublin in 2005.

The song's title is a reference to the chemical defoliant Agent Orange manufactured by Monsanto Corporation and Dow Chemical for the U.S. Department of Defense and used in the Vietnam War. As a guest on the late-night show Last Call with Carson Daly, Michael Stipe explained that the song was about a young American football player leaving the comforts of home for the war in Vietnam. Also, Stipe opened the song during The Green World Tour by singing the famous U.S. Army recruiting slogan, "Be all you can be... in the Army." Stipe's father served in the Vietnam War.

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