"Open Your Heart" is a song by the British synthpop group The Human League. It was released as a single in the UK in September 1981 and peaked at number six in the UK Singles Chart. It was written jointly by lead singer Philip Oakey and keyboard player Jo Callis. The song features a lead vocal by Oakey and female backing vocals by Susanne Sulley and Joanne Catherall, analogue synthesizers by Jo Callis, Philip Adrian Wright and Ian Burden. Drum machines, sequencing and programming were provided by producer Martin Rushent.

"Open Your Heart" was the last of three songs from the Dare album to be released in advance of the album itself. Unlike previous singles "The Sound of the Crowd" and "Love Action (I Believe in Love)", "Open Your Heart" was written specifically for the album Dare. It was chosen by Virgin executive Simon Draper to be Dare's taster single, deliberately issued just in advance of the album. It quickly reached number six in the UK singles chart and raised the band's profile to the highest it had been to that point. Issued only three weeks before Dare, the single acted as a powerful promotional vehicle for the album. The cover artwork and promotional video was deliberately coordinated with its parent album.
It was the first Human League record sleeve to feature new band member Jo Callis, who co-wrote the song with Phil Oakey and who also wrote the B-side "Non-Stop" with Adrian Wright. In an interview in October 2009 Callis said, "I had started to work out both those tunes on guitar, playing along to an early drum machine which had about six preset drum patterns, Open Your Heart did translate better on the keyboard and I think we used the same drum machine with the same preset on the original demo which was done in the League's old 8 track studio in Sheffield".

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