"One Day in Your Life" is a song by American recording artist Anastacia from her second studio album, Freak of Nature. Co-written with and produced by Sam Watters and Louis Biancaniello, the song was released as the album's second single. It was also the only single released in the United States from the album, peaking at number one on the Hot Dance Club Play chart.

"One Day In Your Life" was written by Anastacia and co-written with and produced by Sam Watters and Louis Biancaniello. It is a soulful disco song. It also features a funk synthesizer.

Jose F. Promis written for Allmusic called it "dramatic" and said that "it follows the same formula as her previous hit, 'I'm Outta Love,' but better, with more soaring, epic vocals, and sounds like a rock version of a forgotten disco classic." Mark Bautz from Entertainment Weekly commented that "it has a kicky Flashdance retro vibe." Aidin Vaziri from Rolling Stone called it "a moment of sheer overkill."

Though "One Day in Your Life" never charted on the U.S. Billboard Hot 100, it earned Anastacia her first chart-topper on Billboard's Hot Dance Club Play chart, staying atop for one week. The single fared far better elsewhere, charting within the top ten in Australia and several European countries, including Austria, Germany, Hungary, Italy, the Netherlands, and Switzerland, while peaking at number eleven on the UK Singles Chart.

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