Omnipaque

Iohexol
Clinical data

Trade names	Omnipaque, others
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Pregnancy category	US: B (No risk in non-human studies)
Routes of administration	intrathecal, intravascular, by mouth, intracavital, rectal
ATC code	V08AB02 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding	Low
Metabolism	Nil
Biological half-life	Variable
Excretion	Kidney, unchanged
Identifiers
IUPAC name 1-N,3-N-bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide
Synonyms	5-[N-(2,3-Dihydroxypropyl)acetamido]-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide
CAS Number	66108-95-0^Y
PubChem CID	3730
DrugBank	DB01362^Y
ChemSpider	3599^Y
UNII	4419T9MX03
KEGG	D01817^Y
ChEBI	CHEBI:31709^Y
ChEMBL	CHEMBL1200455^N
ECHA InfoCard	100.060.130
Chemical and physical data
Formula	C₁₉H₂₆I₃N₃O₉
Molar mass	821.138 g/mol
3D model (Jmol)	Interactive image
SMILES O=C(N(c1c(I)c(c(I)c(c1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO)CC(O)CO)C
InChI InChI=1S/C19H26I3N3O9/c1-8(29)25(4-11(32)7-28)17-15(21)12(18(33)23-2-9(30)5-26)14(20)13(16(17)22)19(34)24-3-10(31)6-27/h9-11,26-28,30-32H,2-7H2,1H3,(H,23,33)(H,24,34)^Y Key:NTHXOOBQLCIOLC-UHFFFAOYSA-N^Y
^NY (what is this?)

Iohexol, sold under the trade names Omnipaque among others, is a contrast agent used during X-rays. This includes when visualizing arteries, veins, ventricles of the brain, the urinary system, and joints, as well as during computer tomography (CT scan). It is given by mouth, injection into a vein, or into a body cavity.

Side effects include vomiting, skin flushing, headache, itchiness, kidney problems, and low blood pressure. Less commonly allergic reactions or seizures may occur. It should not be used by those who have a iodine allergy. Use in the later part of pregnancy may cause hypothyroidism in the baby. Iohexol is an iodinated non-ionic radiocontrast agent. It is in the low osmolar family.

Iohexol was approved for medical use in 1985. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 10.99 USD per 50 ml vial. In the United States a dose costs 50 to 100 USD.