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OPCML

OPCML
Identifiers
Aliases OPCML, IGLON1, OBCAM, OPCM, opioid binding protein/cell adhesion molecule-like, opioid binding protein/cell adhesion molecule like
External IDs MGI: 97397 HomoloGene: 55663 GeneCards: OPCML
RNA expression pattern
PBB GE OPCML 206215 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_177906

RefSeq (protein)

n/a

Location (UCSC) Chr 11: 132.41 – 133.53 Mb Chr 9: 27.79 – 28.93 Mb
PubMed search

NM_001319106

NM_177906

NP_002536
NP_002536.1

n/a

Opioid-binding protein/cell adhesion molecule is a protein that in humans is encoded by the OPCML gene.

This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene.




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Wikipedia

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