NuvaRing
| Combination of | |
|---|---|
| Ethinylestradiol | Estrogen |
| Etonogestrel | Progestogen |
| Clinical data | |
| Trade names | NuvaRing |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| MedlinePlus | a604032 |
| Pregnancy category |
|
| Routes of administration |
Vaginal (ring) |
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | 131562-74-8 |
| PubChem (CID) | 9960701 |
| ChemSpider | None |
Ethinylestradiol/etonogestrel (brand names NuvaRing) is a contraceptive vaginal ring containing the estrogen ethinylestradiol and the progestin etonogestrel which is marketed in the United States and Europe.
A study found that users of vaginal rings with ethinylestradiol and etonogestrel have a 6.5 times increased risk of venous thrombosis compared to non-users. This is commensurate with the risk of thrombosis due to the use of combination birth control pills, which in studies ranged between 2.9 times to 13.7 times the risk. As such, contraceptive vaginal rings do not necessarily appear to pose a lower risk of thrombosis than do birth control pills.
A number of lawsuits have been filed alleging the companies involved concealed the health risks associated with using the NuvaRing, which are currently being settled for $100 million.
The ring is placed into the vagina for a three-week period, then removal of the ring for one week, during which the user will experience a menstrual period. The break week is comparable to the placebo week for combined oral contraceptive pills ("the Pill"), and the contraceptive effect is maintained during this period. Extended use regimens (seven-week, quarterly, or annual) involving back-to-back use of (2, 4, or 17) rings have been studied in clinical trials, but are not currently approved.
Insertion of the ring is comparable to insertion of other vaginal rings. The muscles of the vagina keep NuvaRing securely in place, even during exercise or sex. Women can check the contraceptive ring periodically with their finger. In rare instances, NuvaRing may fall out during sexual intercourse, while straining before or during a bowel movement, or while removing a tampon.
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