Nucleolin

NCL
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2FC8, 2FC9, 2KRR
Identifiers
Aliases	NCL, C23, nucleolin
External IDs	MGI: 97286 HomoloGene: 136488 GeneCards: NCL
Gene ontology Molecular function • nucleotide binding • DNA binding • telomeric DNA binding • protein C-terminus binding • protein binding • RNA binding • identical protein binding • nucleic acid binding Cellular component • cytoplasm • membrane • intracellular ribonucleoprotein complex • nucleoplasm • cell cortex • nucleolus • cytoplasmic ribonucleoprotein granule • extracellular exosome • nucleus Biological process • positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter • angiogenesis • positive regulation of transcription from RNA polymerase II promoter • cellular response to epidermal growth factor stimulus Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4691	17975
Ensembl	ENSG00000115053	ENSMUSG00000026234
UniProt	P19338	P09405
RefSeq (mRNA)	NM_005381	NM_010880
RefSeq (protein)	NP_005372	NP_035010.3 NP_035010
Location (UCSC)	Chr 2: 231.45 – 231.48 Mb	Chr 1: 86.34 – 86.36 Mb
PubMed search

2FC8, 2FC9, 2KRR

4691

17975

ENSG00000115053

ENSMUSG00000026234

P19338

P09405

NM_005381

NM_010880

NP_005372

NP_035010.3
NP_035010

Nucleolin is a protein that in humans is encoded by the NCL gene.

The human NCL gene is located on chromosome 2 and consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.

Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. The protein is located mainly in dense fibrillar regions of the nucleolus.

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Wikipedia