Nikola Altomanović (Serbian Cyrillic: Никола Алтомановић) was a 14th-century Serbian župan of the House of Vojinović. He ruled the areas from Rudnik, over Polimlje, Podrinje, east Herzegovina with Trebinje, till Konavle and Dračevica, neighboring the Republic of Dubrovnik. He was defeated and blinded in Užice (fortress Užice) in 1373 by a coalition of his Serbian and Bosnian royals neighbors supported by the king of Hungary.
His father was Altoman, a vojvod in Zeta. In 1363, Nikola's uncle Vojislav Vojinović was killed and Nikola used his uncle's death to gain a piece of his land. He allied himself with Lazar against King Vukašin Mrnjavčević and they managed to persuade Uroš to support them. However, after Lazar pulled out at the critical moment they were defeated at Kosovo in 1369.
In 1373, a military alliance against Nikola was created, which included Bosnian Ban Tvrtko I Kotromanić, Zetan Ruler Đurađ I Balšić, Mačvan Prince Nikola Gorjanski, and Hungarian King Ludovik I. In the same year, they battled against Nikola and Nikola lost, thus his territory was split between Prince Lazar Hrebeljanović of Serbia, Đurađ I Balšić of Zeta, and Ban Tvrtko I Kotromanić of Bosnia.