Neurotrophin-4

NTF4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1HCF, 1B8M, 1B98
Identifiers
Aliases	NTF4, GLC10, GLC1O, NT-4, NT-4/5, NT-5, NT4, NT5, NTF5, neurotrophin 4
External IDs	OMIM: 162662 MGI: 97381 HomoloGene: 4503 GeneCards: NTF4
Gene ontology Molecular function • neurotrophin p75 receptor binding • receptor binding • protein binding • growth factor activity Cellular component • endoplasmic reticulum lumen • extracellular region • cytoplasmic vesicle Biological process • negative regulation of neuron apoptotic process • regulation of neuron differentiation • adult locomotory behavior • sensory organ boundary specification • cell-cell signaling • neuron projection morphogenesis • innervation • negative regulation of cell death • long-term memory • taste bud development • mechanoreceptor differentiation • transmembrane receptor protein tyrosine kinase signaling pathway • ganglion mother cell fate determination • epidermis development Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4909	78405
Ensembl	ENSG00000225950	ENSMUSG00000074121
UniProt	P34130	Q80VU4
RefSeq (mRNA)	NM_006179	NM_198190
RefSeq (protein)	NP_006170	NP_937833
Location (UCSC)	Chr 19: 49.06 – 49.07 Mb	Chr 7: 45.41 – 45.42 Mb
PubMed search

1HCF, 1B8M, 1B98

4909

78405

ENSG00000225950

ENSMUSG00000074121

P34130

Q80VU4

NM_006179

NM_198190

NP_006170

NP_937833

Neurotrophin-4 (NT-4), also known as neurotrophin-5 (NT-5), is a protein that in humans is encoded by the NTF4 gene.

NT-4 is a neurotrophic factor that signals predominantly through the TrkB receptor tyrosine kinase.

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Wikipedia