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Neuropeptide Y

NPY
Neuropeptide Y.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases NPY, PYY4, Neuropeptid Y gene, neuropeptide Y
External IDs OMIM: 162640 MGI: 97374 HomoloGene: 697 GeneCards: NPY
RNA expression pattern
PBB GE NPY 206001 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000905

NM_023456

RefSeq (protein)

NP_000896

NP_075945.1
NP_075945

Location (UCSC) Chr 7: 24.28 – 24.29 Mb Chr 6: 49.82 – 49.83 Mb
PubMed search
Neuropeptide Y
Identifiers
CAS Number 82785-45-3 N
ChemSpider none
ChEMBL CHEMBL267633 N
Chemical and physical data
Formula C190H287N55O57
Molar mass 4253.7 g/mol
 NYesY (what is this?)  

1RON, 1QFA

NM_000905

NM_023456

NP_000896

NP_075945.1
NP_075945

Neuropeptide Y (NPY) is a 36-amino acid neuropeptide that acts as a neurotransmitter in the brain and in the autonomic nervous system of humans; slight variations of the peptide are found in many other animals. In the autonomic system it is produced mainly by neurons of the sympathetic nervous system and serves as a strong vasoconstrictor and also causes growth of fat tissue. In the brain, it is produced in various locations including the hypothalamus, and is thought to have several functions, including: increasing food intake and storage of energy as fat, reducing anxiety and stress, reducing pain perception, affecting the circadian rhythm, reducing voluntary alcohol intake, lowering blood pressure, and controlling epileptic seizures.


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