A neural pathway, is a series of neurons connected together to enable a signal to be sent from one brain region to another. Neurons are connected by a single nerve fibre or by bundles of nerve fibres known as tracts. A neural pathway that serves to connect relatively distant areas of the brain or nervous system is a bundle of neurons, known collectively as white matter. A neural pathway that spans a shorter distance between structures, such as most of the pathways of the major neurotransmitter systems, is usually called grey matter.
In the hippocampus there are neural pathways involved in its circuitry including the perforant pathway, that provides a connectional route from the entorhinal cortex to all fields of the hippocampal formation, including the dentate gyrus, all CA fields (including CA1), and the subiculum.
Descending motor pathways travel form the cerebral cortex to the lower spinal cord.
The first named pathways are evident to the naked eye even in a poorly preserved brain, and were named by the great anatomists of the Renaissance using cadaver material. Examples of these include the great commissures of the brain such as the corpus callosum (Latin, "hard body"; not to be confused with the Latin word "colossus" - the "huge" statue), anterior commissure, and posterior commissure. Further examples include the pyramidal tract, crus cerebri (Latin, "leg of the brain"), and cerebellar peduncles (Latin, "little foot of the cerebellum"). Note that these names describe the appearance of a structure but give one no information on its function or location.