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Neosporin

Neomycin/polymyxin B/bacitracin
Combination of
Polymyxin B sulfate Antibiotic
Neomycin sulfate Antibiotic
Bacitracin zinc Antibiotic
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
License data
Pregnancy
category
  • C
Routes of
administration
Topical
Legal status
Legal status
Identifiers
ChemSpider
  
Neosporin
Product type Antibiotic
Owner Johnson & Johnson
Introduced 1952
Related brands Polysporin
Markets US and Canada
Previous owners Pfizer
Website neosporin.com

Neomycin/polymyxin B/bacitracin sold under the brand name Neosporin among others, is an antibiotic cream that contains neomycin, polymyxin B, and bacitracin. It is used to prevent infections.

Neomycin/polymyxin B/bacitracin ointment is reported to be a safe and effective topical agent for preventing infections in minor skin trauma.

Neosporin is recommended for burns, scratches, cuts, and minor skin infections. It is most effective when affected area is cleaned before application of ointment.

The use of triple-antibiotic ointments, such as neomycin/polymyxin B/bacitracin, decreases infection rates in minor-contaminated wounds. However, if the wound is sterile then there are no benefits.

Neosporin is for external use only and should not go near mucus membranes such as the eyes or mouth. Neosporin is not recommended for children under the age of two. There are no known side effects when using Neosporin, however users should immediately seek medical attention when experiencing hives, rashes, or itching. Any skin irritations such as pain, burning, or cracked skin that were not present prior to use of ointment must receive immediate care.

Concern exists that the use of Neosporin contributes to the emergence of antibiotic-resistant bacteria. In the US, the only large market for Neosporin, the ointment may promote the prevalence of MRSA bacteria, specifically the highly lethal ST8:USA300 strain. Neosporin has been shown to cause contact dermatitis in some cases, and may contribute to antibiotic resistance.

The original ointment contains three different antibiotics: bacitracin, neomycin, and polymyxin B, in a relatively low-molecular-weight patented base of cocoa butter, cottonseed oil, sodium pyruvate, , and petroleum jelly.


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