Neokosmos Grigoriadis (Greek: Νεόκοσμος Γρηγοριάδης, 1879–1967) was a Greek Army general, notable for his involvement in the Greek Resistance during World War II as a leading member of the left-wing National Liberation Front (EAM).
Neokosmos Grigoriadis was born in 1879 in Constantinople, Ottoman Empire (today Istanbul, Turkey) to an ethnic Greek family. He initially graduated from the Greek Army's NCO Academy but eventually he became a regular commissioned officer, and by the end of his military career he had achieved the rank of Major General.
Grigoriadis had an eventful military career. From 1907 to 1909 he was posted in Edessa (then still part of the Ottoman Empire) as a secret agent working against Turkish and Bulgarian interests during the Macedonian Struggle; officially, he was principal of Edessa's Greek primary school.
He took part in the revolutionary Goudi Coup in 1909, fought in the Balkan Wars and World War I, and sided with the Venizelists during the National Schism. In 1920, after the royalist electoral victory, he was discharged from the Army, but he was recommissioned in 1922 by the 11 September 1922 Revolution, and participated in the Trial of the Six as "revolutionary commissioner" (public prosecutor). In 1926 he was promoted to Major General, and later that year left the Army for good.