The area now known as Narellan was probably originally home to the Tharawal people, based in the Illawarra region, although the Western Sydney-based Darug people and the Southern Highlands-based Gandangara people were also known to have inhabited the greater Camden area. Very early relations with British settlers were cordial but as farmers started clearing and fencing the land affecting food resources in the area, clashes between the groups arose until 1816 when a number of indigenous people were massacred and the remainder retreated from direct conflict with the settlers.

In 1805 wool pioneer John Macarthur was granted 5,000 acres (20 km²) at Cowpastures (now Camden). After the land was cleared, it was used for farming for most of the next 200 years until Sydney's suburban sprawl reached the town of Camden and modern suburbs like Narellan were subdivided into housing blocks.

Narellan Post Office opened on 1 August 1856.

Narellan was home to the Oran Park Raceway motor racing circuit, which has been redeveloped into a new residential suburb known as Oran Park Town.

Camden Golf Club is the only golf club in Narellan. Narellan also has a football club known as Narellan Rangers located at Nott Oval.

In the 2011 Australian Bureau of Statistics Census, the suburb of Narellan had a population of 3,492 people. Like its neighbouring suburbs, Narellan is predominantly Australian born (84.5%) families with young children (48%) living in detached houses (90.2%). The number of people aged 65 and over (11.2%) is substantially less than the national average (14%).

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