Nandrolone
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| Pronunciation | /ˈnændrəloʊn/ |
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| Routes of administration |
Intramuscular |
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| Pharmacokinetic data | |
| Bioavailability | 2.24% (Oral) 100% (Intramuscular) |
| Metabolism | Hepatic |
| Biological half-life | 6 days |
| Excretion | ~21 days |
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| Synonyms | Nortestosterone, 19-nortestosterone, 10-nortestosterone, norandrostenolone, nortestosterone, nortestrionate, nortestonate, oestrenolone, estrenolone, SG-4341 |
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| ECHA InfoCard | 100.006.457 |
| Chemical and physical data | |
| Formula | C18H26O2 |
| Molar mass | 274.40 |
| 3D model (Jmol) | |
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  (what is this?)
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Nandrolone (INN, BAN), also known as 19-nortestosterone or 19-norandrostenolone, is a synthetic anabolic-androgenic steroid (AAS) derived from testosterone. The drug itself is inactive orally due to its lack of a 17α-alkyl group (which renders it vulnerable to extensive first-pass metabolism) and is not actually employed in medicine. Instead, nandrolone is used in the form of a variety of long-acting prodrug esters (see nandrolone ester) for intramuscular injection, the most common of which are nandrolone decanoate (Deca-Durabolin, Eubolin, Retabolil) and, to a lesser extent, nandrolone phenylpropionate (Durabolin, Fenobolin).
As of 2009, nandrolone was used clinically, but increasingly rarely, for people in catabolic states who had major burns, cancer, and AIDS, and an ophthalmological formulation was available to support cornea healing.
The positive effects of the drug include muscle growth, appetite stimulation and increased red blood cell production, and bone density. Clinical studies have shown it to be effective in treating anemia, osteoporosis and some forms of neoplasia including breast cancer, and also acts as a progestin-based contraceptive.
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