NRXN1

NRXN1

Protein NRXN1 PDB 1c4r.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3B3Q

Identifiers

NRXN1, Hs.22998, PTHSL2, SCZD17, neurexin 1

External IDs

MGI: 1096391 HomoloGene: 21005 GeneCards: NRXN1

Gene ontology
Molecular function	• metal ion binding • calcium-dependent protein binding • neuroligin family protein binding • receptor binding • transmembrane signaling receptor activity • cell adhesion molecule binding • protein binding • calcium ion binding • acetylcholine receptor binding • receptor activity • calcium channel regulator activity
Cellular component	• integral component of membrane • vesicle • nuclear membrane • membrane • endocytic vesicle • axonal growth cone • synapse • cell surface • cell junction • neuronal cell body • endoplasmic reticulum • presynaptic membrane • plasma membrane • integral component of presynaptic membrane • integral component of plasma membrane • protein complex
Biological process	• calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules • receptor localization to synapse • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules • NMDA glutamate receptor clustering • establishment of protein localization • neuron cell-cell adhesion • gamma-aminobutyric acid receptor clustering • neuronal signal transduction • gephyrin clustering involved in postsynaptic density assembly • postsynaptic density protein 95 clustering • learning • regulation of AMPA receptor activity • negative regulation of filopodium assembly • presynaptic membrane assembly • regulation of NMDA receptor activity • vocalization behavior • neuroligin clustering involved in postsynaptic membrane assembly • adult behavior • positive regulation of synaptic transmission, glutamatergic • postsynaptic membrane assembly • cell adhesion • angiogenesis • positive regulation of excitatory postsynaptic potential • social behavior • guanylate kinase-associated protein clustering • synapse assembly • protein complex assembly involved in synapse maturation • synaptic vesicle clustering • protein localization to synapse • signal transduction • cerebellar granule cell differentiation • positive regulation of synapse assembly • positive regulation of presynaptic active zone assembly • positive regulation of protein localization to plasma membrane • vocal learning • chemical synaptic transmission • regulation of insulin secretion involved in cellular response to glucose stimulus • axon guidance • prepulse inhibition • neuromuscular process controlling balance • positive regulation of synapse maturation • neurotransmitter secretion • regulation of grooming behavior • regulation of molecular function
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE NRXN1 209915 s at fs.png

PBB GE NRXN1 209914 s at fs.png

PBB GE NRXN1 216096 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


9378


18189


n/a


ENSMUSG00000024109


P58400 Q9ULB1 Q49A31


P0DI97 Q9CS84

RefSeq (mRNA)

NM_001135659 NM_004801 NM_138735 NM_001320156 NM_001320157
NM_001330077 NM_001330078 NM_001330079 NM_001330081 NM_001330082 NM_001330083 NM_001330084 NM_001330085 NM_001330086 NM_001330087 NM_001330088 NM_001330089 NM_001330090 NM_001330091 NM_001330092 NM_001330093 NM_001330094 NM_001330095 NM_001330096 NM_001330097

NM_020252 NM_177284 NM_001346957 NM_001346958 NM_001346959
NM_001346960 NM_001346961 NM_001346962 NM_001347419

RefSeq (protein)

NP_620072.1 NP_001129131.1 NP_004792.1 NP_620072.1 NP_004792.1
NP_004792.1 NP_620072.1


NP_064648.3 NP_796258.2

Location (UCSC)

n/a

Chr 17: 90.03 – 91.09 Mb

PubMed search

n/a

ENSMUSG00000024109

P58400
Q9ULB1
Q49A31

NM_001330077
NM_001330078
NM_001330079
NM_001330081
NM_001330082
NM_001330083
NM_001330084
NM_001330085
NM_001330086
NM_001330087
NM_001330088
NM_001330089
NM_001330090
NM_001330091
NM_001330092
NM_001330093
NM_001330094
NM_001330095
NM_001330096
NM_001330097

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Wikipedia

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