NOL3

NOL3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UZ0
Identifiers
Aliases	NOL3, ARC, FCM, MYP, NOP, NOP30, nucleolar protein 3
External IDs	MGI: 1925938 HomoloGene: 31208 GeneCards: NOL3
Gene ontology Molecular function • death effector domain binding • calcium ion binding • death receptor binding • metal ion binding • cysteine-type endopeptidase inhibitor activity involved in apoptotic process • protein binding • RNA binding • identical protein binding • receptor binding • caspase binding Cellular component • cytosol • membrane • sarcoplasmic reticulum • sarcoplasm • nucleus • mitochondrion • nucleolus • cytoplasm Biological process • regulation of apoptotic process • release of sequestered calcium ion into cytosol by sarcoplasmic reticulum • response to hypoxia • negative regulation of striated muscle cell apoptotic process • inhibition of cysteine-type endopeptidase activity involved in apoptotic process • negative regulation of tumor necrosis factor-mediated signaling pathway • negative regulation of muscle atrophy • negative regulation of release of cytochrome c from mitochondria • response to injury involved in regulation of muscle adaptation • negative regulation of extrinsic apoptotic signaling pathway • mRNA processing • negative regulation of apoptotic process • cardiac muscle cell apoptotic process • intrinsic apoptotic signaling pathway • negative regulation of cardiac muscle cell apoptotic process • blood vessel remodeling • response to ischemia • mRNA splice site selection • protein oligomerization • negative regulation of mitochondrial membrane permeability involved in apoptotic process • regulation of gene expression • negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway • regulation of NF-kappaB import into nucleus • negative regulation of necrotic cell death • apoptotic process • RNA splicing Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8996	78688
Ensembl	ENSG00000140939	ENSMUSG00000014776
UniProt	O60936	Q9D1X0
RefSeq (mRNA)	NM_001185057 NM_001185058 NM_001276307 NM_001276309 NM_001276311 NM_001276312 NM_001276319 NM_003946	NM_030152
RefSeq (protein)	NP_001171986 NP_001171987 NP_001263236 NP_001263238 NP_001263240 NP_001263241 NP_001263248 NP_003937	NP_084428.1 NP_084428
Location (UCSC)	Chr 16: 67.17 – 67.18 Mb	Chr 8: 105.28 – 105.28 Mb
PubMed search

4UZ0

8996

78688

ENSG00000140939

ENSMUSG00000014776

O60936

Q9D1X0

NM_001276312
NM_001276319
NM_003946

NM_030152

NP_001263241
NP_001263248
NP_003937

NP_084428.1
NP_084428

Nucleolar protein 3 is a protein that in humans is encoded by the NOL3 gene.

NOL3 has been shown to interact with SFRS9 and Caspase 8.

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Wikipedia