NLGN2

NLGN2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3BL8
Identifiers
Aliases	NLGN2, neuroligin 2
External IDs	MGI: 2681835 HomoloGene: 69317 GeneCards: NLGN2
Gene location (Human) Chr. Chromosome 17 (human) Band 17p13.1 Start 7,404,874 bp End 7,419,860 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 B3 Start 69,823,122 bp End 69,837,784 bp
Gene ontology Molecular function • carboxylic ester hydrolase activity • neurexin family protein binding • cell adhesion molecule binding • receptor activity Cellular component • integral component of membrane • postsynaptic membrane • membrane • synapse • inhibitory synapse • cell surface • cell junction • presynaptic membrane • plasma membrane • integral component of plasma membrane • integral component of postsynaptic membrane • intracellular Biological process • single organismal cell-cell adhesion • neuromuscular process controlling balance • neuron cell-cell adhesion • positive regulation of inhibitory postsynaptic potential • synapse organization • modulation of chemical synaptic transmission • positive regulation of protein localization to synapse • gephyrin clustering involved in postsynaptic density assembly • postsynaptic density protein 95 clustering • positive regulation of synaptic transmission, GABAergic • regulation of AMPA receptor activity • locomotory exploration behavior • regulation of respiratory gaseous exchange by neurological system process • cell-cell junction maintenance • positive regulation of synaptic vesicle clustering • positive regulation of synaptic transmission, glutamatergic • cell adhesion • positive regulation of excitatory postsynaptic potential • sensory perception of pain • terminal button organization • protein localization to synapse • positive regulation of insulin secretion • positive regulation of synapse assembly • inhibitory synapse assembly • synapse assembly • synaptic vesicle endocytosis • postsynaptic membrane assembly • presynaptic membrane assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	57555	216856
Ensembl	ENSG00000169992 ENSG00000283859	ENSMUSG00000051790
UniProt	Q8NFZ4	Q69ZK9
RefSeq (mRNA)	NM_020795	NM_198862
RefSeq (protein)	NP_065846	NP_942562
Location (UCSC)	Chr 17: 7.4 – 7.42 Mb	Chr 17: 69.82 – 69.84 Mb
PubMed search

3BL8

57555

216856

ENSG00000169992
ENSG00000283859

ENSMUSG00000051790

Q8NFZ4

Q69ZK9

NM_020795

NM_198862

NP_065846

NP_942562

Neuroligin-2 is a protein that in humans is encoded by the NLGN2 gene.

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.

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Wikipedia