NFKB2

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1A3Q, 2D96, 3DO7, 4OT9

Identifiers

NFKB2, CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52, p100, p49/p100, nuclear factor kappa B subunit 2

External IDs

Gene ontology
Molecular function	• DNA binding • transcription factor activity, sequence-specific DNA binding • transcription coactivator activity • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • chromatin binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • protein binding
Cellular component	• cytoplasm • Bcl3/NF-kappaB2 complex • nucleus • nucleoplasm • cytosol
Biological process	• response to cytokine • regulation of transcription, DNA-templated • rhythmic process • germinal center formation • aging • extracellular matrix organization • negative regulation of transcription from RNA polymerase II promoter • spleen development • transcription, DNA-templated • follicular dendritic cell differentiation • response to lipopolysaccharide • NIK/NF-kappaB signaling • positive regulation of NF-kappaB transcription factor activity • inflammatory response • I-kappaB kinase/NF-kappaB signaling • positive regulation of type I interferon production • positive regulation of transcription from RNA polymerase II promoter • signal transduction • transcription from RNA polymerase II promoter • innate immune response
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


4791


18034


ENSG00000077150


ENSMUSG00000025225


Q00653


Q9WTK5

RefSeq (mRNA)

NM_001077494 NM_001261403 NM_001288724 NM_002502 NM_001322934
NM_001322935


NM_001177369 NM_001177370 NM_019408

RefSeq (protein)

NP_001070962 NP_001248332 NP_001275653 NP_001309863 NP_001309864
NP_002493


NP_001170840.1 NP_062281.1 NP_001170840 NP_001170841 NP_062281

Location (UCSC)

PubMed search

Nuclear factor NF-kappa-B p100 subunit is a protein that in humans is encoded by the NFKB2 gene.