NFATC2

NFATC2

Protein NFATC2 PDB 1a02.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1A02, 1OWR, 1P7H, 1PZU, 2AS5, 2O93, 3QRF

Identifiers

NFATC2, NFAT1, NFATP, nuclear factor of activated T-cells 2

External IDs

MGI: 102463 HomoloGene: 7861 GeneCards: NFATC2

Genetically Related Diseases

amyotrophic lateral sclerosis

Gene ontology
Molecular function	• DNA binding • sequence-specific DNA binding • transcription factor activity, sequence-specific DNA binding • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • transcription factor binding • chromatin binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding • protein binding • transcription regulatory region DNA binding • transcription regulatory region sequence-specific DNA binding • RNA polymerase II transcription factor activity, sequence-specific DNA binding
Cellular component	• cytoplasm • nuclear transcription factor complex • transcription factor complex • intracellular ribonucleoprotein complex • nucleoplasm • nucleus • nuclear chromatin • cytosol
Biological process	• B cell receptor signaling pathway • regulation of transcription, DNA-templated • cytokine production • calcineurin-NFAT signaling cascade • negative regulation of transcription from RNA polymerase II promoter • transcription from RNA polymerase II promoter • myotube cell development • transcription, DNA-templated • cellular response to DNA damage stimulus • positive regulation of transcription, DNA-templated • Fc-epsilon receptor signaling pathway • positive regulation of myoblast fusion • positive regulation of gene expression • positive regulation of B cell proliferation • cell migration • response to drug • positive regulation of transcription from RNA polymerase II promoter
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


4773


18019


ENSG00000101096


ENSMUSG00000027544


Q13469


Q60591

RefSeq (mRNA)

NM_001136021 NM_001258292 NM_001258294 NM_001258295 NM_001258296
NM_001258297 NM_012340 NM_173091

NM_001037177 NM_001037178 NM_001136073 NM_001291168 NM_001291169
NM_001291170 NM_001291171 NM_001291172 NM_001291173 NM_001291174 NM_001291175 NM_001291176 NM_001291177 NM_001291178 NM_001291179 NM_010899

RefSeq (protein)

NP_001129493 NP_001245221 NP_001245223 NP_001245224 NP_001245225
NP_001245226 NP_036472 NP_775114

NP_035029.2 NP_001032254 NP_001032255 NP_001129545 NP_001278097
NP_001278098 NP_001278099 NP_001278100 NP_001278101 NP_001278102 NP_001278103 NP_001278104 NP_001278105 NP_001278106 NP_001278107 NP_001278108 NP_035029

Location (UCSC)

Chr 20: 51.39 – 51.56 Mb

Chr 2: 168.48 – 168.6 Mb

PubMed search

1A02, 1OWR, 1P7H, 1PZU, 2AS5, 2O93, 3QRF

ENSG00000101096

ENSMUSG00000027544

NM_001258297
NM_012340
NM_173091

NM_001291170
NM_001291171
NM_001291172
NM_001291173
NM_001291174
NM_001291175
NM_001291176
NM_001291177
NM_001291178
NM_001291179
NM_010899

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Wikipedia

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