NFATC1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1A66, 1NFA

Identifiers

NFATC1, NF-ATC, NFAT2, NFATc, NF-ATc1.2, nuclear factor of activated T-cells 1

External IDs

Gene ontology
Molecular function	• RNA polymerase II distal enhancer sequence-specific DNA binding • DNA binding • RNA polymerase II regulatory region sequence-specific DNA binding • RNA polymerase II transcription factor binding • transcription factor activity, sequence-specific DNA binding • mitogen-activated protein kinase p38 binding • FK506 binding • transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding • protein binding • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding • RNA polymerase II transcription coactivator binding
Cellular component	• cytoplasm • cytosol • nuclear chromatin • nucleus • nucleoplasm • nuclear body
Biological process	• intracellular signal transduction • regulation of transcription, DNA-templated • calcineurin-NFAT signaling cascade • transcription from RNA polymerase II promoter • transcription, DNA-templated • positive regulation of transcription, DNA-templated • Fc-epsilon receptor signaling pathway • positive regulation of transcription from RNA polymerase II promoter • Wnt signaling pathway, calcium modulating pathway
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


4772


18018


ENSG00000131196


ENSMUSG00000033016


O95644


O88942

RefSeq (mRNA)

NM_172390 NM_001278669 NM_001278670 NM_001278672 NM_001278673
NM_001278675 NM_006162 NM_172387 NM_172388 NM_172389

NM_001164109 NM_001164110 NM_001164111 NM_001164112 NM_016791
NM_198429

RefSeq (protein)

NP_001265598 NP_001265599 NP_001265601 NP_001265602 NP_001265604
NP_006153 NP_765975 NP_765976 NP_765977 NP_765978


n/a

Location (UCSC)

PubMed search

n/a

Nuclear factor of activated T-cells, cytoplasmic 1 is a protein that in humans is encoded by the NFATC1 gene.