N,O-Dimethylhydroxylamine

N,O-Dimethylhydroxylamine

Names
IUPAC name N-Methoxymethanamine
Other names Methoxymethylamine; Methylmethoxyamine; HNMeOMe
Identifiers
CAS Number	1117-97-1 Y 6638-79-5 (HCl) N
3D model (JSmol)	Interactive image
ChemSpider	13596 N
ECHA InfoCard	100.012.960
PubChem CID	14232
InChI InChI=1S/C2H7NO/c1-3-4-2/h3H,1-2H3 N Key: KRKPYFLIYNGWTE-UHFFFAOYSA-N N InChI=1/C2H7NO/c1-3-4-2/h3H,1-2H3 Key: KRKPYFLIYNGWTE-UHFFFAOYAP
SMILES CNOC
Properties
Chemical formula	C2H7NO
Molar mass	61.08 g·mol−1
Melting point	−97 °C (−143 °F; 176 K) Hydrochloride salt: 112 to 115 °C (234 to 239 °F; 385 to 388 K)
Boiling point	43.2
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YN ?)
Infobox references

N,O-Dimethylhydroxylamine is a methylated hydroxylamine used to form so called 'Weinreb amides' for use in the Weinreb ketone synthesis. It is commercially available as its hydrochloride salt.

It may be prepared by reacting ethyl chloroformate (or similar) with hydroxylamine followed by treatment with a methylating agent such as dimethyl sulfate. The N,O-dimethylhydroxylamine is then liberated by acid hydrolysis followed by neutralization.