Myocyte-specific enhancer factor 2A

MEF2A

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1C7U, 1EGW, 1LEW, 3KOV, 3MU6, 3P57

Identifiers

Aliases

MEF2A, ADCAD1, RSRFC4, RSRFC9, mef2, myocyte enhancer factor 2A

External IDs

MGI: 99532 HomoloGene: 4080 GeneCards: MEF2A

Gene ontology
Molecular function	• sequence-specific DNA binding • RNA polymerase II transcription coactivator activity • DNA binding • protein dimerization activity • RNA polymerase II transcription factor binding • transcription factor activity, sequence-specific DNA binding • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • histone deacetylase binding • chromatin binding • activating transcription factor binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • protein binding • histone acetyltransferase binding • protein heterodimerization activity • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding • RNA polymerase II transcription factor activity, sequence-specific DNA binding • SMAD binding • protein kinase binding • RNA polymerase II regulatory region sequence-specific DNA binding
Cellular component	• transcription factor complex • nucleoplasm • nuclear chromatin • nucleus • cytosol
Biological process	• cellular response to calcium ion • cell differentiation • regulation of transcription, DNA-templated • mitochondrial genome maintenance • dendrite morphogenesis • positive regulation of muscle cell differentiation • muscle organ development • negative regulation of transcription from RNA polymerase II promoter • GO:0006350 transcription, DNA-templated • nervous system development • ERK5 cascade • multicellular organism development • positive regulation of transcription, DNA-templated • heart development • cardiac conduction • mitochondrion distribution • ventricular cardiac myofibril assembly • positive regulation of transcription from RNA polymerase II promoter • apoptotic process • positive regulation of cardiac muscle hypertrophy • transcription from RNA polymerase II promoter • MAPK cascade
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


4205


17258

Ensembl


ENSG00000068305


ENSMUSG00000030557

UniProt


Q02078


Q60929

RefSeq (mRNA)

NM_001130926 NM_001130927 NM_001130928 NM_001171894 NM_005587
NM_001319206


NM_001033713 NM_001291191 NM_001291192 NM_001291195 NM_001291196

RefSeq (protein)

NP_001124398 NP_001124399 NP_001124400 NP_001165365 NP_001306135
NP_005578

NP_001028885.1 NP_001278120.1 NP_001278121.1 NP_001278124.1 NP_001278125.1
NP_001028885 NP_001278120 NP_001278121 NP_001278124 NP_001278125

Location (UCSC)

Chr 15: 99.57 – 99.72 Mb

Chr 7: 67.23 – 67.37 Mb

PubMed search

1C7U, 1EGW, 1LEW, 3KOV, 3MU6, 3P57

NM_001033713
NM_001291191
NM_001291192
NM_001291195
NM_001291196

NP_005578

NP_001028885
NP_001278120
NP_001278121
NP_001278124
NP_001278125

...
Wikipedia