Myelin-PO_C | |||||||||
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Identifiers | |||||||||
Symbol | Myelin-PO_C | ||||||||
Pfam | PF10570 | ||||||||
InterPro | IPR019566 | ||||||||
OPM superfamily | 230 | ||||||||
OPM protein | 3oai | ||||||||
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Available protein structures: | |
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Pfam | structures |
PDB | RCSB PDB; PDBe; PDBj |
PDBsum | structure summary |
MPZ | |||||||||||||||||
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Identifiers | |||||||||||||||||
Aliases | MPZ, CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, P0, myelin protein zero | ||||||||||||||||
External IDs | OMIM: 159440 MGI: 103177 HomoloGene: 445 GeneCards: MPZ | ||||||||||||||||
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RNA expression pattern | |||||||||||||||||
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Orthologs | |||||||||||||||||
Species | Human | Mouse | |||||||||||||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | Chr 1: 161.3 – 161.31 Mb | Chr 1: 171.15 – 171.16 Mb | |||||||||||||||
PubMed search | |||||||||||||||||
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NM_008623
NM_001315499
NM_001315500
NP_001302428
NP_001302429
NP_032649
Myelin protein zero (P0, MPZ) is a glycoprotein which in humans is encoded by the MPZ gene. P0 is a major structural component of the myelin sheath, and its deficiency due to various mutations in the MPZ gene is associated with Charcot–Marie–Tooth disease and Dejerine–Sottas disease.