Mutant is the fifth album by Twiztid. Released on July 26, 2005, it is the second half of the Man's Myth/Mutant double album, released one month after its companion album, Man's Myth. On November 4, 2015, Twiztid announced they were remixing and remastering Mutant for a 2016 re-release.

While Man's Myth featured a hip hop-oriented sound, Mutant featured a rock oriented sound. According to Jamie Spaniolo, "I've always wanted to do a Rock album and to date that was the closest thing to it we have ever done, so it holds a special place in my heart."

Allrovi said that "the sound of this album is far closer to Eminem's side of the Detroit hip-hop axis, specifically the cartoonish but musically fierce live-instruments-plus-samples sound of the best D12 tracks."

Allrovi wrote that Mutant was better than its predecessor, Man's Myth; Allrovi also said that Mutant is "the best album of Twiztid's career, [...] the one on which the duo finally steps out from the shadow of their mentors the Insane Clown Posse".

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