Mu-Ming Poo
| Mu-ming Poo | |
|---|---|
| Native name | 蒲慕明 (Pu Muming) |
| Born |
October 31, 1948 Nanjing, Jiangsu, China |
| Alma mater |
National Tsing Hua University, Johns Hopkins University |
| Known for | Pioneering work on synaptic plasticity, first true cloning of primates |
| Spouse(s) | Wen-jen Hwu (divorced) |
| Children | 2, including Ai-jen Poo |
| Awards | Gruber Prize in Neuroscience (2016) |
| Scientific career | |
| Fields | Neuroscience |
| Institutions | Institute of Neuroscience (ION) of the Chinese Academy of Sciences, University of California, Berkeley |
Mu-ming Poo or Pu Muming (Chinese: 蒲慕明; born October 31, 1948) is a Chinese-American neuroscientist. He is Paul Licht Distinguished Professor Emeritus at the University of California, Berkeley and the Founding Director of the Shanghai-based Institute of Neuroscience (ION) of the Chinese Academy of Sciences. He was awarded the 2016 Gruber Prize in Neuroscience for his pioneering work on synaptic plasticity. At ION, Poo led a team of scientists that produced the world's first truly cloned primates, a pair of crab-eating macaques called Zhongzhong and Huahua in 2017, using somatic cell nuclear transfer (SCNT).
Poo was born in Nanjing, Jiangsu, China on October 31, 1948. When he was one, his family moved to Taiwan because of the Chinese Communist Revolution. Influenced by his father, an aeronautical engineer, he was interested in physics from a young age. He attended National Tsing Hua University in Taiwan, graduating with a degree in physics in 1970.
In 1970, he went to the United States to pursue graduate studies at Johns Hopkins University, where he became interested in biophysics. Under the guidance of Professor Richard Cone, he developed the now widely used method to determine the kinetics of diffusion through cells, fluorescence recovery after photobleaching. His research was published in the major journal Nature in 1974. After earning his PhD, he was a postdoctoral researcher at Purdue University, and became an assistant professor at the University of California, Irvine in 1976. He developed a new method to manipulate proteins in cell membranes called "in situ electrophoresis".
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