The Mountain Valley Conference (MVC) was an athletic conference consisting of 6 large high schools and 4 School Districts from Monroe County and the Lehighton Area School District from Carbon County, Pennsylvania in the United States. It was part of District XI of the Pennsylvania Interscholastic Athletic Association (PIAA).
There had been widespread discussion about high school league realignment in the Lehigh Valley starting in late 1990 or early 1991. It was in the fall of 1993 that the formation of the Mountain Valley Conference was announced. The new league comprised all the public high schools in Monroe County at the time: Stroudsburg, East Stroudsburg, Pocono Mountain, and Pleasant Valley High Schools, plus Nazareth and Northampton High Schools from Northampton County. Lehighton Area High School would also join the new league, giving it an initial membership of seven schools when competition began with the 1994-95 school year.
After the 1997-98 school year, the MVC added more schools in Lehigh and Northampton Counties: Easton Area, Freedom, Liberty, Parkland, and Whitehall all joined the league. After 2001-02 the seven schools in Lehigh and Northampton Counties left the league to help form the Lehigh Valley Conference. East Stroudsburg school district had opened a new high school near the turn of the century, and Pocono Mountain district opened a new high school in 2002; both new schools were added to the MVC for the start of the 2002-03 school year. MVC membership has been stable from 2002 to 2012.